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Novel chimeric proteins made of a globin domain fused with a "cofactor free" monooxygenase domain have been identified within the Streptomyces avermitilis and Frankia sp. genomes by means of bioinformatics methods. Structure based sequence alignments...
The enzyme S-norcoclaurine synthase (SNCS) catalyzes the stereoselective Pictet-Spengler cyclization between dopamine and 4-hydroxyphenylacetaldehyde, the key step in benzylisoquinoline alkaloids biosynthetic pathway. The crystallographic structure o...